Dr. Iadecola is a clinician-scientist who is an internationally recognized expert in the field of neurovascular regulation, cerebrovascular diseases and dementia. His research focuses on the basic mechanisms by which the brain suffers and dies when its blood supply is compromised, leading to stroke and cognitive impairment, and in developing new therapies for these devastating conditions.
Dr. Iadecola received an MD degree from the University of Rome, Italy, in 1977, wherein he pursued neurology training with Prof. Cesare Fieschi. In 1980, he joined Cornell University first as a post-doctoral fellow with Dr. Donald Reis, and then as Neurology Resident with Dr. Fred Plum. In 1990, Dr. Iadecola joined the Department of Neurology of the University of Minnesota. He rose through the academic ranks serving as Professor and Vice-Chair for Research from 1997 to 2001. In 2001, Dr. Iadecola was recruited back to Cornell as the G. C. Cotzias Distinguished Professor of Neurology and Neuroscience, and Director of the Division of Neurobiology, a post previously held by his mentor Dr. Reis. In 2012 Dr. Iadecola was appointed Anne Parrish Titzell Professor of Neurology and Director of the Feil Family Brain and Mind Research Institute, the largest basic science department at Weill Cornell focused on basic and translational neuroscience research.
Research and awards
Dr. Iadecola’s research deals with the mechanisms of normal and abnormal cerebrovascular regulation, and on the molecular pathology of ischemic brain injury and neurodegeneration. A major area of interest relates to the interactions between cardiovascular risk factors, stroke and Alzheimer’s disease. His laboratory is a fertile training ground for junior faculty, post-doctoral fellows, graduate and medical students. Dr. Iadecola has published over 300 papers in peer-reviewed journals. He is active in several national and international research organizations and funding agencies. He has served on the Research Committee and on the Stroke Council of the American Heart Association (AHA) and chaired the Program Committee of the International Stroke Conference. He participates in focus groups and review committees at the NIH. He has been President (Chair) of the Scientific Advisory Committee of the Fondation Leducq and is an advisor to the European Stroke Networks, the Institute of Stroke and Dementia Research (Munich, Germany), the Cluster for Systems Neurology (Munich, Germany), the Hotchkiss Brain Institute (Calgary, Canada), the DHU NeuroVascular disease Sorbonne (Paris, France), and the TargetBrain European Union Consortium. Dr. Iadecola has served as Associate Editor, Consulting Editor for the AHA journal Stroke, and Reviewing Editor for the Journal of Neuroscience, the official journal of the Society for Neuroscience. He serves as Guest Editor for Hypertension, Circulation and for the Proceeding of the National Academy of Sciences. He is a member of the editorial board of the Annals of Neurology, Circulation Research, Cerebrovascular Diseases, Cellular and Molecular Neuroscience, and the Journal of Cerebral Blood Flow and Metabolism. He has received the McHenry Award from the American Academy of Neurology, the Louis Sklarow Memorial Award, the Established Investigator Award (AHA), two Jacob Javits Awards from NINDS/NIH (1999, 2015), and the Willis Award, the highest honor in stroke research bestowed by the AHA. In 2011, Dr. Iadecola received the Zenith Fellow Award from the Alzheimer’s Association in support of his efforts to elucidate the role of vascular factors in Alzheimer’s dementia. Elected to the Association of American Physicians in 2015, he also received the 2015 AHA Award for Excellence in Hypertension Research, which recognizes researchers who have had a major impact in the field of hypertension and contributed to a greater understanding of high blood pressure. He is the principal investigator of several NIH grants, and of grants from the Leducq Foundation, and the Leon Levy Foundation